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HDAC3-IN-1

HDAC3-IN-1 (compound 5) is a potent and selective HDAC3 inhibitor, with an IC50 of 5.96 nM[1].

Product Specifications

CAS Number

2044701-99-5

Product Name Alternative

GMX1778

UNSPSC

12352005

Hazard Statement

H225-H319

Target

HDAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/hdac3-in-1.html

Solubility

10 mM in DMSO

Smiles

O=C(/C=C/C1=CC=CC=C1)NCC2=CC=C(C=C2)C(NNCCC)=O

Molecular Formula

C20H23N3O2

Molecular Weight

337.42

Precautions

P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P370+P378-P403+P235-P501

References & Citations

[1]Moreno-Yruela C, Olsen CA. Determination of Slow-Binding HDAC Inhibitor Potency and Subclass Selectivity. ACS Med Chem Lett. 2022 Mar 16;13 (5) :779-785.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

HDAC1; HDAC2; HDAC3

Available Sizes

Frequently Asked Questions

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