4A3-SC10
4A3-SC10 is an ionizable cationic lipid (pKa = 6.57) utilized in the formation of lipid nanoparticles (LNPs) for mRNA delivery both in vitro and in vivo. In mice, these LNPs, which contain 4A3-SC10, preferentially accumulate in the liver, kidney, and spleen. Furthermore, LNPs with 4A3-SC10 that encapsulate an mRNA reporter stimulate reporter expression in 4T1 breast cancer cells, B16/F10 melanoma cells, and AML12 hepatocytes.
Product Specifications
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS1255521-01 0.02 mg (E-Coli)
Recombinant Cyanophora paradoxa Uncharacterized 5.7 kDa protein in psbM-psbX intergenic region
Sign In for Pricing
View Details MBS1255521-02 0.1 mg (E-Coli)
Recombinant Cyanophora paradoxa Uncharacterized 5.7 kDa protein in psbM-psbX intergenic region
Sign In for Pricing
View Details MBS1255521-03 0.02 mg (Yeast)
Recombinant Cyanophora paradoxa Uncharacterized 5.7 kDa protein in psbM-psbX intergenic region
Sign In for Pricing
View Details MBS1255521-04 0.1 mg (Yeast)
Recombinant Cyanophora paradoxa Uncharacterized 5.7 kDa protein in psbM-psbX intergenic region
Sign In for Pricing
View Details 
MBS1255521-05 0.02 mg (Baculovirus)
Recombinant Cyanophora paradoxa Uncharacterized 5.7 kDa protein in psbM-psbX intergenic region
Sign In for Pricing
View Details