Cytosine β-D-arabinofuranoside Hydrochloride

<strong>Cytosine β-D-arabinofuranoside Hydrochloride</strong>_x000D_ <strong>Catalog number:</strong> B2017797_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 279.68 g/mol_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8°C_x000D_ <strong>Keywords:</strong> 1-(β-D-Arabino­furanosyl)­cytosine hydrochloride, Ara-C hydrochloride, Arabinocytidine hydrochloride, Arabinosylcytosine hydrochloride, Cytarabine hydrochloride, Cytosine arabinoside hydrochloride_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Wang Q, Hu W, Wang S, Pan Z, Tao L, Guo X, Qian K, Chen CH, Lee KH, Chang J. Synthesis of new 2'-deoxy-2'-fluoro-4'-azido nucleoside analogues as potent anti-HIV agents Eur J Med Chem. 2011 Sep;46(9):4178-83._x000D_ 2: Manna S, Kirtana R, Roy A, Baral T, Patra SK. Mechanisms of hedgehog, calcium and retinoic acid signalling pathway inhibitors: Plausible modes of action along the MLL-EZH2-p53 axis in cellular growth control Arch Biochem Biophys. 2023 Jul 1;742:109600._x000D_ 3: Iizumi T, Takahashi S, Mashima K, Minami K, Izawa Y, Abe T, Hishiki T, Suematsu M, Kajimura M, Suzuki N. A possible role of microglia-derived nitric oxide by lipopolysaccharide in activation of astroglial pentose-phosphate pathway via the Keap1/Nrf2 system J Neuroinflammation. 2016 May 4;13(1):99._x000D_ 4: Grichnik JM, Burch JA, Schulteis RD, Shan S, Liu J, Darrow TL, Vervaert CE, Seigler HF. Melanoma, a tumor based on a mutant stem cell? J Invest Dermatol. 2006 Jan;126(1):142-53._x000D_ 5: Cytarabine 2024 May 15. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–._x000D_ 6: González-Burguera I, Ricobaraza A, Aretxabala X, Barrondo S, García del Caño G, López de Jesús M, Sallés J. Highly efficient generation of glutamatergic/cholinergic NT2-derived postmitotic human neurons by short-term treatment with the nucleoside analogue cytosine β-D-arabinofuranoside Stem Cell Res. 2016 Mar;16(2):541-51._x000D_ 7: Ko LW, Kulathingal JG, Yen SH. Cytosine beta-D-arabinofuranoside used as a paradigm modifier to increase production of tau aggregates in a cellular model of tauopathy Neurochem Res. 2007 Apr-May;32(4-5):823-32._x000D_ 8: Sidi Y, Panet C, Cyjon A, Fenig E, Beery E, Nordenberg J. Guanosine potentiates the antiproliferative effect of cytosine-beta-D-arabinofuranoside in melanoma cell lines Cancer Invest. 1993;11(5):523-9._x000D_ 9: Boyer SH, Sun Z, Jiang H, Esterbrook J, Gómez-Galeno JE, Craigo W, Reddy KR, Ugarkar BG, MacKenna DA, Erion MD. Synthesis and characterization of a novel liver-targeted prodrug of cytosine-1-beta-D-arabinofuranoside monophosphate for the treatment of hepatocellular carcinoma J Med Chem. 2006 Dec 28;49(26):7711-20._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/6124381">10: Parker RJ, Priester ER, Sieber SM. Comparison of lymphatic uptake, metabolism, excretion, and biodistribution of free and liposome-entrapped [14C]cytosine beta-D-arabinofuranoside following intraperitoneal administration to rats Drug Metab Dispos. 1982 Jan-Feb;10(1):40-6.</a>_x000D_ _x000D_ <strong>Products Related to Cytosine β-D-arabinofuranoside Hydrochloride can be found at</strong> <a href="https://moleculardepot.com/product-category/Chemicals/"> Chemicals</a>