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SR10098

SR10098 is a high-affinity ligand for the NR4A nuclear receptor family that exhibits significant activating activity toward Nurr1 (NR4A2) (EC50 = 24 nM) and modulatory effects on other members of the NR4A family (Nur77, Nor1) . Nurr1 is involved in regulating the development, survival, and maintenance of dopaminergic neurons. Therefore, SR10098 can be used in research on Parkinson’s disease (PD) and neurodegenerative disorders.

Product Specifications

CAS Number

850705-30-5

Smiles

O=C (O) C1=CC=C2N=C (NC2=C1) C=3C=CC (F) =CC3

Molecular Formula

C14H9FN2O2

Molecular Weight

256.23

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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