YW2065
YW2065 has excellent anti-colorectal cancer effects in vitro and in vivo. YW2065 achieves its inhibitory activity for Wnt signaling by stabilizing Axin-1, a scaffolding protein that regulates proteasome degradation of β-catenin. Simultaneously, YW2065 also led to the activation of the tumor suppressor AMPK, providing an additional anticancer mechanism. In addition, YW2065 showed favorable pharmacokinetic properties without obvious toxicity.
Product Specifications
CAS Number
2131223-85-1
Smiles
CC=1N (N=CC1C (NC2=NC3=C (C=C2) C=CC=C3) =O) C4=C (Br) C=CC=C4
Molecular Formula
C20H15BrN4O
Molecular Weight
407.26
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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