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2-O-Methylcytosine

2-O-Methylcytosine is an O-alkylated DNA adduct and is recognized as a damaged nucleobase. As an analogue of cytosine, it acts as a human endogenous metabolite. The presence of 2-O-Methylcytosine can alter the structural stability and base-pairing properties of DNA. The accumulation of such damaged nucleobases is closely linked to the induction of DNA mutations, which may result in various diseases, including cancer.

Product Specifications

CAS Number

3289-47-2

Purity

99.54% (May vary between batches)

Smiles

N=1C=CC (=NC1OC) N

Molecular Formula

C5H7N3O

Molecular Weight

125.13

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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