OPC-14523 dihydrochloride
OPC-14523 dihydrochloride is the dihydrochloride form of the free base OPC-14523. OPC-14523 dihydrochloride is an orally active dual agonist of sigma receptors and 5-HT1A receptors that also inhibits the 5-HT transporter, with IC50 values of 47/56 nM for sigma receptors σ1/2, 5-HT1A receptor IC50 = 2.3 nM, and 5-HT transporter IC50 = 80 nM. OPC-14523 dihydrochloride exhibits antidepressant-like activity. OPC-14523 dihydrochloride can be used in neuroscience research, including studies on antidepressants and neuroprotection.
Product Specifications
Purity
99.70% (May vary between batches)
Smiles
COc1c2c (N (C (CC2) =O) CCCN3CCN (c4cc (Cl) ccc4) CC3) ccc1.Cl.Cl
Molecular Formula
C23H30Cl3N3O2
Molecular Weight
486.86
Storage Conditions
-20°C
Notes
For research use only.
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