JKE-1716
JKE-1716 is an inhibitor of glutathione peroxidase 4 (GPX4) and a derivative of the GPX4 inhibitor ML-210 .1JKE-1716 reduces viability of LOX-IMVI cancer cells in a concentration-dependent manner and in a panel of additional cancer cell lines, an effect that can be blocked by the ferroptosis inhibitor ferrostatin-1 .
Product Specifications
CAS Number
2421118-05-8
Smiles
O\N=C (\CC (=O) N1CCN (CC1) C (c1ccc (Cl) cc1) c1ccc (Cl) cc1) [N+] ([O-]) =O
Molecular Formula
C20H20Cl2N4O4
Molecular Weight
451.3
Storage Conditions
-20°C
Notes
For research use only.
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