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JKE-1716

JKE-1716 is an inhibitor of glutathione peroxidase 4 (GPX4) and a derivative of the GPX4 inhibitor ML-210 .1JKE-1716 reduces viability of LOX-IMVI cancer cells in a concentration-dependent manner and in a panel of additional cancer cell lines, an effect that can be blocked by the ferroptosis inhibitor ferrostatin-1 .

Product Specifications

CAS Number

2421118-05-8

Smiles

O\N=C (\CC (=O) N1CCN (CC1) C (c1ccc (Cl) cc1) c1ccc (Cl) cc1) [N+] ([O-]) =O

Molecular Formula

C20H20Cl2N4O4

Molecular Weight

451.3

Storage Conditions

-20°C

Notes

For research use only.

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