Isovaleryl-L-carnitine (chloride)
Isovaleryl-L-carnitine is a naturally occurring acylcarnitine that is formed via metabolic conversion of L-leucine. It increases survival and decreases apoptosis in hepatocyte growth factor-deprived murine C2.8 hepatocytes when used at a concentration of 1 mM. Isovaleryl-L-carnitine inhibits amino acid deprivation-induced proteolysis and autophagy in isolated perfused rat liver when used at concentrations of 77 and 100 μM, respectively. Increased levels of isovaleryl carnitine are associated with isovaleryl-CoA dehydrogenase deficiency (isovaleric acidemia) .
Product Specifications
CAS Number
139144-12-0
Purity
99.95% (May vary between batches)
Smiles
[C@H] (OC (CC (C) C) =O) (C[N+] (C) (C) C) CC (O) =O.[Cl-]
Molecular Formula
C12H24ClNO4
Molecular Weight
281.78
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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