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TNG961

TNG961 is a potent, highly selective, CRBN-dependent HBS1L (GSPT3) molecular chaperone inhibitor. By degrading HBS1L, TNG961 specifically disrupts protein homeostasis in FOCAD-deficient cancer cells, thereby inducing growth inhibition and cell death. TNG961 can be used in studies of FOCAD-deficient tumors.

Product Specifications

Smiles

O=C ([C@H] (CC1) C2=CC3=CC=CC (NC (NC (C) (C) C4=CC5=C (C=C (C (F) (F) F) C=C5) S4) =O) =C3C=C2) NC1=O

Molecular Formula

C28H24F3N3O3S

Molecular Weight

539.57

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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