LSKL, Inhibitor of Thrombospondin (TSP-1)
Selected Variant
HY-P0299-01
Size: 1 mg
LSKL, Inhibitor of Thrombospondin (TSP-1) is a latency-associated protein (LAP) -TGFβ derived tetrapeptide and a competitive TGF-β1 antagonist. LSKL, Inhibitor of Thrombospondin (TSP-1) inhibits the binding of TSP-1 to LAP and alleviates renal interstitial fibrosis and hepatic fibrosis. LSKL, Inhibitor of Thrombospondin (TSP-1) suppresses subarachnoid fibrosis via inhibition of TSP-1-mediated TGF-β1 activity, prevents the development of chronic hydrocephalus and improves long-term neurocognitive defects following subarachnoid hemorrhage (SAH) . LSKL, Inhibitor of Thrombospondin (TSP-1) can readily crosse the blood-brain barrier[1][2].
Product Specifications
CAS Number
283609-79-0
UNSPSC
12352209
Target
TGF-β Receptor
Type
Peptides
Related Pathways
TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/LSKL,_Inhibitor_of_Thrombospondin_TSP-1.html
Purity
99.84
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)
Smiles
CC(C)C[C@@H](C(N)=O)NC([C@H](CCCCN)NC([C@H](CO)NC([C@H](CC(C)C)N)=O)=O)=O
Molecular Formula
C21H42N6O5
Molecular Weight
458.60
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Citation 01
Available Sizes
Price
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Human IL-2/Interleukin-2 ELISA Kit PicoKine®
CD44 / HCAM Std. (HCAM/2875R), CF640R conjugate, 0.1mg/mL
Anti-Cytochrome P450 2E1/CYP2E1 Antibody Picoband®
Ferritin, Light Chain (FTL) (Microglia Marker) (FTL/1388), CF568 conjugate, 0.1mg/mL
