PROTAC CDK2/4/6 Degrader-2
PROTACCDK2/4/6 Degrader-2 is a PROTAC degrader specifically targeting CDK2/4/6. It can react in a single step with pivaloyl chloride to convert into the prodrug PROTACCDK2/4/6 Degrader-1. In malignant melanoma cells, this compound effectively degrades CDK2/4/6 proteins and their complexes, leading to cell cycle arrest and apoptosis, with a pronounced effect on melanoma cells. PROTACCDK2/4/6 Degrader-2 is valuable for related malignant melanoma research.
Product Specifications
CAS Number
2541626-49-5
Smiles
O=C (NCCCCCCNC1=CC=CC=2C (=O) N (C (=O) C12) C3C (=O) NC (=O) CC3) C4=CC=C (C=C4) NC=5N=CC=6C=C (C (=O) N (C) C) N (C6N5) C7CCCC7
Molecular Formula
C40H45N9O6
Molecular Weight
747.86
Storage Conditions
-20°C
Notes
For research use only.
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