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ZD-1-186

ZD-1-186 is a non-degradable molecular glue that effectively inhibits MYC expression in diffuse large B-cell lymphoma cells and significantly induces the expression of CDKN1A (p21) . This compound facilitates the binding of BCL6 to BRD9, a non-canonical BAF complex bromodomain protein involved in sustaining MYC transcriptional activity in certain lymphoma contexts. ZD-1-186 is applicable for research in targeted transcriptional reprogramming.

Product Specifications

Storage Conditions

-20°C

Notes

For research use only.

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