PROTAC HDAC4 Degrader-1
PROTACHDAC4 Degrader-1 (compound SCT-1) is a potent and selective PROTACHDAC4 degrader. It effectively reduces HDAC4 protein levels, induces S phase cell cycle arrest, and inhibits colony formation, leading to the suppression of tumor cell proliferation. The compound has demonstrated inhibitory activity in the H460 mouse model and is applicable in cancer research, including studies of lung cancer.
Product Specifications
CAS Number
3036245-14-1
Smiles
O=C1C2=CC=C (C=C2C (=O) N1C3C (=O) NC (=O) CC3) N4CCN (C (=O) CCCCCCCCOC5=C (C (=O) N (C6=CC=C (C=C6) C (F) (F) F) C) C (=O) N (C=7C=CC=C (OC) C57) C) CC4
Molecular Formula
C46H49F3N6O9
Molecular Weight
886.93
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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