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TMU454

TMU454 is a prototype GalNAc-PROTAC conjugate. It binds to ASGPR on the cell membrane and is internalized through ASGPR-mediated endocytosis. TMU454 selectively degrades BRD4 and exhibits anticancer activity against hepatocellular carcinoma.

Product Specifications

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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