NEP108
NEP108 is a BRD4 PROTAC degrader designed based on GID4 E3 ligase, with a DC50 of approximately 3.8 μM. It exhibits strong affinity for GID4, with a KD value of 0.22 μM, and a ternary complex KD value of 2.85 μM. NEP108 can be utilized for cancer research.
Product Specifications
CAS Number
3031840-31-7
Smiles
CC=1C2=C (N3C ([C@H] (CC (NCCOCCOC=4C=C5C (=CC4) N=C (N5) [C@@H]6CC[C@H] (NC (CNCC7=CC=8C (N7) =CC=CC8) =O) CC6) =O) N=C2C9=CC=C (Cl) C=C9) =NN=C3C) SC1C
Molecular Formula
C47H51ClN10O4S
Molecular Weight
887.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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