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PROTAC EGFR degrader 17

PROTACEGFRdegrader 17 (Compound 35) is an EGFR PROTAC degrader with a DC50 value of 0.49 nM. It facilitates the ubiquitination and degradation of EGFR and can be used for research in various cancers, including non-small cell lung cancer.

Product Specifications

CAS Number

3065209-64-2

Smiles

O=C1\N=C/2\N (C=3C (N2) =CC=C (C3) N4CCN (CC5CN (C5) C=6C=C7C (=CC6) C (=O) N (C7) C8C (=O) NC (=O) CC8) CC4) C[C@]9 (C[C@] (CC9) (COC%10=C (C%11=CC1=CC (C) =N%11) C=NN%10C) [H]) [H]

Molecular Formula

C46H51N11O5

Molecular Weight

837.99

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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