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PROTAC HDAC8 Degrader-3

PROTACHDAC8 Degrader-3 (Compound BP1) is a potent and selective HDAC8 PROTAC degrader with a DC50 of 20 nM. It exhibits IC50 values of 0.46 μM for HDAC8 and 7.5 μM for CRBN. PROTACHDAC8 Degrader-3 shows strong antiproliferative activity against MM.1S and HL-60 cells, and it is applicable in the study of multiple myeloma and acute myeloid leukemia.

Product Specifications

Storage Conditions

-20°C

Notes

For research use only.

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