ZFYV1 rabbit pAb
The FYVE domain mediates the recruitment of proteins involved in membrane trafficking and cell signaling to phosphatidylinositol 3-phosphate-containing membranes. This protein contains two zinc-binding FYVE domains in tandem and is reported to localize to the Golgi apparatus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013],
Product Specifications
Background
The FYVE domain mediates the recruitment of proteins involved in membrane trafficking and cell signaling to phosphatidylinositol 3-phosphate-containing membranes. This protein contains two zinc-binding FYVE domains in tandem and is reported to localize to the Golgi apparatus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
UniProt
Q9HBF4
Swiss Prot
Q9HBF4
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human ZFYV1 AA range: 318-368
Target
ZFYV1
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Golgi apparatus, Golgi stack . Golgi apparatus . Endoplasmic reticulum . Lipid droplet . Preautophagosomal structure . Mitochondrion . Resides predominantly in the cisternal stacks of the Golgi (PubMed:11256955) . Colocalizes with TRIM13 on the perinuclear endoplasmic reticulum (PubMed:22178386) . During starvation conditions, localizes to omegasomes which are endoplasmic reticulum connected strutures at the origin of preautophagosomal structures (PubMed:31293035, PubMed:25876663) . Localizes to lipid droplets in the presence of oleic acid (PubMed:31293035, PubMed:30970241) . .
Gene ID (Human)
53349
Available Sizes
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