Voriconazole
Voriconazole (UK-109496) is a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. Voriconazole exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes[1][2].
Product Specifications
CAS Number
[137234-62-9]
Product Name Alternative
UK-109496
UNSPSC
12352005
Hazard Statement
H317, H319
Target
Bacterial; Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Cancer
Assay Protocol
https://www.medchemexpress.com/Voriconazole.html
Purity
99.89
Solubility
DMSO : ≥ 50 mg/mL|H2O : 0.17 mg/mL (ultrasonic)
Smiles
O[C@@]([C@@H](C)C1=NC=NC=C1F)(CN2N=CN=C2)C(C(F)=C3)=CC=C3F
Molecular Formula
C16H14F3N5O
Molecular Weight
349.31
Precautions
H317, H319
References & Citations
[1]Nickie D Greer, et al. Voriconazole: the newest triazole antifungal agent.Proc (Bayl Univ Med Cent) . 2003 Apr;16 (2) :241-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
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