What is the catalog number for MS99-β-Gal?

The catalog number for MS99-β-Gal is orb3176823.

What sizes are available for MS99-β-Gal?

MS99-β-Gal is available in the following size(s): 25 mg, 50 mg, 100 mg.

How many pack sizes does MS99-β-Gal come in?

MS99-β-Gal is available in 3 different pack sizes.

Is MS99-β-Gal in stock?

MS99-β-Gal is currently made to order / not held in immediate stock. Contact us for lead time.

MS99-β-Gal

MS99-β-Gal (Gal-MS99) is a galactose-modified NPM-ALK PROTAC degrader. It is selectively hydrolyzed by SA-β-galactosidase (SA-β-gal) and esterases specifically in senescent cancer cells, releasing MS99, which targets the degradation of the NPM-ALK fusion protein. In senescent Karpas 299 cells, MS99-β-Gal has an IC50 value of 454.8 nM, significantly lower than its IC50 of 2.162 μM in normal Karpas 299 cells. This compound is applicable in cancer research.

Product Specifications

CAS Number

3055593-63-7

Smiles

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