AJM 290
AJM 290 is a Trx-1 inhibitor. AJM 290 is an inhibitor of the HIF-1α COOH-terminal transactivation domain, and blocks HIF-1 binding to DNA[1].
Product Specifications
CAS Number
840474-95-5
UNSPSC
12352005
Target
HIF/HIF Prolyl-Hydroxylase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ajm-290.html
Smiles
O=C1C=CC(C=C1)(C2=CC3=C(N2S(=O)(C4=CC=CC=C4)=O)C=C(F)C=C3)O
Molecular Formula
C20H14FNO4S
Molecular Weight
383.39
References & Citations
[1]Martin AR, et al. Hypoxia inducible factor down-regulation, cancer and cancer stem cells (CSCs) : ongoing success stories. Medchemcomm. 2016 Oct 19;8 (1) :21-52.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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