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PROTAC USP7 Degrader-2

PROTACUSP7 Degrader-2 (Compound D16) is a potent and selective USP7 PROTAC degrader with a DC50 of 1.91 μM (in TE-12 cells) . It inhibits the migration of upper gastrointestinal (UGI) cancer cells while exhibiting weak antiproliferative activity. This compound is utilized for research on metastatic UGI cancer.

Product Specifications

CAS Number

3056612-67-7

Smiles

Cl.O=C1C=CN (C (=O) N1CC=2SC=3C (=NC=CC3C4=CC (Cl) =CC (=C4NC5CNCCC5) C) C2) CCCCCNC6=CC=CC=7C (=O) N (C (=O) C67) C8C (=O) NC (=O) CC8

Molecular Formula

C42H44Cl2N8O6S

Molecular Weight

859.82

Storage Conditions

-20°C

Notes

For research use only.

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