PROTAC ALK degrader-4
PROTACALK degrader-4 (Compound B8) is an ALKPROTAC degrader with a DC50 of 445.25 nM. It demonstrates significant antiproliferative activity against NCI-H2228 and NCI-H3122 cell lines. This compound causes a substantial downregulation of 390 proteins, including IGF-1R and its downstream proteins, such as ERK1/2 and STAT3. PROTACALK degrader-4 is applicable in lung adenocarcinoma research.
Product Specifications
Storage Conditions
-20°C
Notes
For research use only.
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