LD-110
LD-110 is a potent PROTAC degrader targeting LSD1 with a DC50 of 0.44 μM. It promotes LSD1 degradation via a ubiquitin-proteasome-dependent mechanism and enhances H3K4 dimethylation levels. By inducing apoptosis, LD-110 inhibits the growth and survival of various esophageal squamous cell carcinoma (ESCC) cell lines. It is applicable for research on esophageal squamous cell carcinoma.
Product Specifications
Storage Conditions
-20°C
Notes
For research use only.
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