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HRZ-01-082-5

HRZ-01-082-5 is a Glutarimide analog that functions as a bifunctional molecular glue degrader, capable of degrading SALL4 and OSR1, with a DC50 of 4.8 nM for OSR1. It significantly induces the degradation of SALL4 and OSR1 via CRBN. HRZ-01-082-5 is applicable in studies of cardiac and urogenital system development and cancer research.

Product Specifications

CAS Number

3090685-19-8

Smiles

O=C1NC (=O) C (N2C (=O) C3=CC=C (C=C3C2=O) C=4N=C5SC=NN5C4NC67CC8CC (CC (C8) C6) C7) CC1

Molecular Formula

C27H26N6O4S

Molecular Weight

530.6

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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