PROTAC BCL6 Degrader-2
PROTACBCL6 Degrader-2 (Compound A19) is an orally active, selective BCL6 PROTAC degrader with an IC50 of 34 pM in OCI-LY1 cells and 0.45 nM in HEK293T cells. It facilitates the ubiquitination and degradation of BCL6, exhibiting anticancer activity against BCL6-dependent diffuse large B-cell lymphoma. [Pink: BCL6 ligand; Blue: E3 ligase ligand; E3 ligase ligand + linker.]
Product Specifications
Storage Conditions
-20°C
Notes
For research use only.
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