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SMARCA2/4 degrader-1

SMARCA2/4 degrader-1 (Compound 1) is a molecular glue degrader specifically targeting SMARCA2/4, with a DC50 for SMARCA4 of 2.2 nM. It functions by covalently recruiting CUL4DCAF16 and CRL1FBXO22 to facilitate the degradation of SMARCA2/4.

Product Specifications

CAS Number

2901804-87-1

Smiles

OC1=CC=CC=C1C=2N=NC (N) =C (C2) N3CC4N (C=5C=CN=C (C#CCN6CCCCCC6) C5) C (C3) CC4

Molecular Formula

C30H35N7O

Molecular Weight

509.66

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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