SMARCA2/4 degrader-1
SMARCA2/4 degrader-1 (Compound 1) is a molecular glue degrader specifically targeting SMARCA2/4, with a DC50 for SMARCA4 of 2.2 nM. It functions by covalently recruiting CUL4DCAF16 and CRL1FBXO22 to facilitate the degradation of SMARCA2/4.
Product Specifications
CAS Number
2901804-87-1
Smiles
OC1=CC=CC=C1C=2N=NC (N) =C (C2) N3CC4N (C=5C=CN=C (C#CCN6CCCCCC6) C5) C (C3) CC4
Molecular Formula
C30H35N7O
Molecular Weight
509.66
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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