PROTAC OSBP Degrader-1
PROTACOSBP Degrader-1 (Compound 5) is a PROTAC degrader of oxysterol-binding protein (OSBP) with a DC50 of 322 nM at 24 hours. It efficiently penetrates cells and induces significant recruitment of OSBP at the trans-Golgi network. This compound exhibits potent anticancer activity and demonstrates strong cytotoxicity against U-87 MG, A549, MCF7, HeLa, and MDA-MB-231 cells.
Product Specifications
Storage Conditions
-20°C
Notes
For research use only.
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