BI033
BI033 is a selective inhibitor of BTB and CNC homology 1 (BACH1) that specifically binds to the N-terminal of BACH1 with a dissociation constant (Kd) of 9.0 μM. It interferes with the interaction between BACH1 and HDAC1, increases H3K27 acetylation at BACH1 target genes, and promotes the expression of angiogenic genes, indicating its potential therapeutic use for myocardial infarction and ischemic vascular diseases.
Product Specifications
Storage Conditions
-20°C
Notes
For research use only.
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