SLR080811
SLR080811 is a guanidine-based selective inhibitor of sphingosine kinase 2 (SphK2) with a Ki value of 1.3 μM, demonstrating approximately 10-fold selectivity over SphK1 (Ki = 12 μM) . In vitro, it reduces sphingosine-1-phosphate (S1P) levels, but in mice, it can induce SphK1-dependent S1P level increases. SLR080811 is applicable in cancer and fibrosis research.
Product Specifications
CAS Number
1449765-65-4
Smiles
C (=N) (N) N1[C@H] (CCC1) C2=NC (=NO2) C3=CC=C (CCCCCCCC) C=C3
Molecular Formula
C21H31N5O
Molecular Weight
369.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LV814119 1.0 µg DNA
LINC00597 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)
Sign In for Pricing
View Details MBS1056471-01 0.02 mg (E-Coli)
Recombinant Thioalkalivibrio sp. Adenylosuccinate synthetase (purA)
Sign In for Pricing
View Details MBS1056471-02 0.02 mg (Yeast)
Recombinant Thioalkalivibrio sp. Adenylosuccinate synthetase (purA)
Sign In for Pricing
View Details MBS1056471-03 0.1 mg (E-Coli)
Recombinant Thioalkalivibrio sp. Adenylosuccinate synthetase (purA)
Sign In for Pricing
View Details MBS1056471-04 0.1 mg (Yeast)
Recombinant Thioalkalivibrio sp. Adenylosuccinate synthetase (purA)
Sign In for Pricing
View Details MBS1056471-05 0.02 mg (Baculovirus)
Recombinant Thioalkalivibrio sp. Adenylosuccinate synthetase (purA)
Sign In for Pricing
View Details