SLR080811
SLR080811 is a guanidine-based selective inhibitor of sphingosine kinase 2 (SphK2) with a Ki value of 1.3 μM, demonstrating approximately 10-fold selectivity over SphK1 (Ki = 12 μM) . In vitro, it reduces sphingosine-1-phosphate (S1P) levels, but in mice, it can induce SphK1-dependent S1P level increases. SLR080811 is applicable in cancer and fibrosis research.
Product Specifications
CAS Number
1449765-65-4
Smiles
C (=N) (N) N1[C@H] (CCC1) C2=NC (=NO2) C3=CC=C (CCCCCCCC) C=C3
Molecular Formula
C21H31N5O
Molecular Weight
369.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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