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11β-HSD1-IN-25

11β-HSD1-IN-25 is a selective and orally bioavailable inhibitor of 11β-HSD1. It effectively reduces glucocorticoid levels in vitro and in serum, while also diminishing lipid accumulation in both in vitro and in vivo models. 11β-HSD1-IN-25 modulates lipid metabolism through a dual mechanism: inhibiting 11β-HSD1 and activating the AMP-activated protein kinase (AMPK) signaling pathway. This compound is valuable for research on obesity and related metabolic disorders in vivo.

Product Specifications

CAS Number

1261266-23-2

Smiles

C (\C1=C (C (F) (F) F) C=CC=C1F) =C\2/C (=O) \C (=C\C3=C (C (F) (F) F) C=CC=C3F) \CC2

Molecular Formula

C21H12F8O

Molecular Weight

432.31

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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