Tyrosinase-IN-47

Tyrosinase-IN-47 (compound 6a) is a potent competitive inhibitor of tyrosinase with an IC50 of 1.43 μM and a Ki value of 0.1142 μM. It also exhibits inhibitory activity against α-Glucosidase (IC50= 36.26 μM) and acetylcholinesterase (IC50= 8.26 μM) . Additionally, Tyrosinase-IN-47 has in vitro antioxidant activity, demonstrating effective scavenging abilities for DPPH (IC50= 4.75 μM) and ABTS (IC50= 0.04 μM) . Furthermore, it prevents browning in freshly cut potato slices. This compound is applicable in pharmaceutical research.