C-Kit-IN-13
C-Kit-IN-13 (Compound I) is an inhibitor of the c-kit kinase. It suppresses the autophosphorylation of the wild-type c-kit, with an IC50 of 0.3 nM for pKIT. Additionally, c-Kit-IN-13 inhibits Exon 11 KIT with an IC50 of 0.9 nM. This compound can be utilized in research on mast cell-mediated diseases such as urticaria.
Product Specifications
CAS Number
3041025-10-6
Smiles
O=C (NC=1C=C (C=2N=NN (N2) C3CC3) C (F) =CC1C) C=4C=NN5C=CC (=CC45) C6=CN (N=C6C) CC (O) (C) C
Molecular Formula
C27H28FN9O2
Molecular Weight
529.58
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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