CML-07-119
CML-07-119 is a selective inhibitor of GGPP synthase (GGPPS) with an IC50 value of approximately 27 nM. It induces apoptosis and exhibits anticancer activity against acute myeloid leukemia (AML) cells, including those with TP53 mutations. CML-07-119 also suppresses tumor growth in AML mouse xenograft models and is applicable in AML research.
Product Specifications
CAS Number
2241548-12-7
Smiles
O=C (NC1=CC=C (OC) C (F) =C1) C2=CC=CC (=C2) C=3N=C4SC=CC4=C (N3) NC (P (=O) (O) O) P (=O) (O) O
Molecular Formula
C21H19FN4O8P2S
Molecular Weight
568.41
Storage Conditions
-20°C
Notes
For research use only.
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