CZh226 hydrochloride
CZh226 hydrochloride is a potent and selective inhibitor of PAK4, with an IC50 of 18 nM and a selectivity of 346-fold over PAK1. The oral bioavailability of CZh226 hydrochloride is poor, necessitating the use of the prodrug PAK4-IN-1 to enhance absorption and metabolic stability. It is applicable in research on colorectal cancer and melanoma.
Product Specifications
CAS Number
2231440-94-9
Smiles
N (C=1C2=C (N=C (C (=O) N3C[C@@H] (C) NCC3) N1) C=CC (Cl) =C2) C=4C=C (NN4) C5CC5.Cl
Molecular Formula
C20H23Cl2N7O
Molecular Weight
448.35
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Mouse Monoclonal PTH Antibody (3H9 + PTH/1175) [Alexa Fluor 594]](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
NBP2-47731AF594 0.1 mL
Mouse Monoclonal PTH Antibody (3H9 + PTH/1175) [Alexa Fluor 594]
Sign In for Pricing
View Details abx235195 100 µg
Mitochondrial Intermediate Peptidase (MIPEP) Antibody
Sign In for Pricing
View Details 
KZB44162-01 50 mg
2- (5-Amino-1H-indol-1-yl) -N, N-diethylacetamide hydrochloride
Sign In for Pricing
View Details KZB44162-02 0.5 g
2- (5-Amino-1H-indol-1-yl) -N, N-diethylacetamide hydrochloride
Sign In for Pricing
View Details