Aβ/tau aggregation-IN-4
Aβ/tau aggregation-IN-4 (Compound D21) is an inhibitor of Aβ/tau aggregation. It promotes the degradation of Aβ40/42 with IC50 values of 2.151 μM for Aβ40 and 3.622 μM for Aβ42. This compound selectively inhibits AChE with an IC50 of 5.56 μM and also inhibits MAO-A and MAO-B with IC50 values of 0.59 μM and 0.09 μM, respectively. Additionally, Aβ/tau aggregation-IN-4 reduces intracellular ROS levels and is used in Alzheimer's disease research.
Product Specifications
CAS Number
3105860-83-8
Smiles
O=C1C=2C (OC=C1/C=N/NC (=O) C3=C (O) C=C (O) C=C3) =CC=C (O) C2
Molecular Formula
C17H12N2O6
Molecular Weight
340.29
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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