Oltipraz metabolite M2

Oltipraz metabolite M2 is the active metabolite of Oltipraz and acts as an orally effective HIF-1α inhibitor. In a high-fat diet mouse model, it enhances mitochondrial fuel oxidation and suppresses hepatic lipogenesis by dual activation of AMPK. Oltipraz metabolite M2 is applicable for research in hepatic steatosis and fatty liver disease.