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N-Nitroso-tris-chloroethylurea

N-nitroso-tris-chloroethylurea (NTCU) is employed to chemically induce a model of lung squamous cell carcinoma. When applied to the skin of five mouse strains (SWR/J, NIH Swiss, A/J, BALB/cJ, and FVB/J), NTCU resulted in the development of lung squamous cell carcinoma. However, three other strains (AKR/J, 129/svJ, and C57BL/6J) showed no sensitivity to NTCU.

Product Specifications

CAS Number

69113-01-5

Smiles

O=NN (C (=O) N (CCCl) CCCl) CCCl

Molecular Formula

C7H12Cl3N3O2

Molecular Weight

276.54

Storage Conditions

-20°C

Notes

For research use only.

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