Myosin-IN-5
Myosin-IN-5 (Example 3) is a myosin inhibitor with an IC50 of 1.84 μM against bovine cardiac myosin. It demonstrates strong selectivity between cardiac and skeletal muscle myosins, exhibiting IC50 values of 43.4 μM for bovine cardiac myofibrils and 1.5 μM for rabbit skeletal muscle myofibrils. This compound is useful in researching hypertrophic cardiomyopathy (HCM) .
Product Specifications
CAS Number
2839464-02-5
Smiles
O=C1N (C (=O) N=C (N[C@@H] (C) C2=C (F) C=C (F) C=C2) N1) C3CCOCC3
Molecular Formula
C16H18F2N4O3
Molecular Weight
352.34
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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