AP21998
AP21998 is a selective ligand for the Fm (mutant FKBP) domain that binds to a single FKBPv. It disrupts FKBP-mediated oligomerization, inhibits the proliferation of transformed myeloid progenitors, and promotes their terminal myeloid differentiation. AP21998 destabilizes aggregates of CAD-hM1 receptor fusion proteins, allowing receptors to exit the endoplasmic reticulum and reach the plasma membrane. AP21998 is applicable in cancer research.
Product Specifications
CAS Number
292606-90-7
Smiles
[C@H] (C (=O) N1[C@H] (C (O[C@H] (CCC2=CC (OC) =C (OC) C=C2) C3=CC (OCC (NCCCN (C) C) =O) =CC=C3) =O) CCCC1) (CC) C4=CC (OC) =C (OC) C (OC) =C4
Molecular Formula
C43H59N3O10
Molecular Weight
777.96
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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