α-Synuclein-IN-18
α-Synuclein-IN-18 (Compound Mol D) is an inhibitor of the autocatalytic proliferation of α-synuclein (α-Synuclein) aggregates. It selectively binds to a conserved binding pocket on the surface of α-synuclein fibrils, delaying the aggregation process and tripling the aggregation T1/2. Furthermore, α-Synuclein-IN-18 reduces the formation of toxic α-synuclein oligomers, thereby mitigating neurotoxicity. This compound is valuable for Parkinson's disease research.
Product Specifications
CAS Number
1394328-54-1
Smiles
O=C (O) C1NCCC=2NC (=NC21) C3=CNC4=C3C=CC=C4C
Molecular Formula
C16H16N4O2
Molecular Weight
296.33
Storage Conditions
-20°C
Notes
For research use only.
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