(E), (Z) -RNF5 agonist 1
(E), (Z) -RNF5 agonist 1 (Compound Analog-1) is an RNF5 agonist that enhances the ubiquitin-mediated degradation of the SARS-CoV-2 E protein. It effectively inhibits SARS-CoV-2 replication and significantly reduces lung pathology and systemic inflammation in mouse infection models. Additionally, (E), (Z) -RNF5 agonist 1 exhibits potent cytotoxicity against neuroblastoma and melanoma cells. This compound is relevant for cancer and antiviral research.
Product Specifications
CAS Number
2231731-82-9
Smiles
N (\C (=N\C1=CC=CC=C1) \C2=CC=CC=C2) =C\3/N (C (C) =NS3) C4=CC=CC=C4
Molecular Formula
C22H18N4S
Molecular Weight
370.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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