D-myo-Inositol-1,3,4,5,6-pentaphosphate sodium

D-myo-Inositol-1,3,4,5,6-pentaphosphate sodium (Ins (1,3,4,5,6) P5 sodium) is an intracellular signaling molecule. It inhibits the PI3K/Akt signaling pathway, suppressing the phosphorylation and kinase activity of Akt/PKB, which induces apoptosis in cancer cells. Additionally, it inhibits endothelial cell tubular structure formation in an in vitro angiogenesis mouse model. This compound is employed in research on ovarian cancer, lung cancer, breast cancer, and cardiovascular diseases involving angiogenesis inhibition.