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MWAC-3429

MWAC-3429 is a potent inhibitor of the SARS-CoV-2 Nsp13 helicase. It demonstrates inhibitory effects on SARS-CoV-2 and SARS-CoV-1 with EC50 values of 5.39 μM (nLuc assay) and 17.00 μM (CPE assay), respectively. The compound also displays low cytotoxicity in A549-hACE2 cells (CC50 > 50 μM) . MWAC-3429 is useful for research on SARS-CoV infections.

Product Specifications

CAS Number

2093677-54-2

Smiles

O=C (C=1N=C (SC1) CCN) N2CC3=CC (OC) =CC=C3CC2C=4C=CC=CC4

Molecular Formula

C22H23N3O2S

Molecular Weight

393.51

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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