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Pitstop 2c

Pitstop 2c is a Clathrin inhibitor with an IC50 of less than 2 μM. It binds to the Clathrin N-terminal β-propeller domain, impairing Clathrin's function and dynamics, and blocking the entry of vesicular stomatitis virus (VSV) . Pitstop 2c inhibits clathrin-mediated endocytosis (Endocytosis) but does not inhibit non-clathrin-dependent endocytosis.

Product Specifications

Storage Conditions

-20°C

Notes

For research use only.

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