PDE2A-IN-2
PDE2A-IN-2 is a selective blood-brain barrier-permeable PDE2A inhibitor (Ki = 5.49 nM) with over 100-fold selectivity for other PDE subtypes. The 11C-labeled PDE2A-IN-2 can be utilized as a positron emission tomography (PET) tracer for imaging in neurodegenerative diseases. In vitro, PDE2A-IN-2 reduces the signal of radiotracers in PDE2A-rich areas, while in vivo, it shows lower binding affinity. It is applicable in research focused on neurodegenerative conditions.
Product Specifications
CAS Number
2055901-03-4
Smiles
FC (F) (F) C1=CC=C (C=C1) C2 (NC3=NC (=NC4=C3C=NN4C) C) CC2
Molecular Formula
C17H16F3N5
Molecular Weight
347.35
Storage Conditions
-20°C
Notes
For research use only.
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